| Laboratory Studies |
|
|
| Skin Irritation Test |
| Skin irritation test of the contract of Argeria Speiosa Extract was studied at B.V Patel Pharmaceutical Education Research and Development Centre (PERD) by using Sprague Dawley Rabbits as model. Following data shows their evaluation and conclusion. |
| |
| Evaluation |
| The following tables show the data that had been evaluated at the PERD centre. |
| Visual Scores For Skin Irritation Test |
|
Animal No.
|
SCORE FOR TEST COMPOUND
|
|
Erythema and Escher formation
|
Edema
|
| 0 hr |
48 hrs |
0 hr |
48 hrs |
| 1 |
0 |
0 |
0 |
0 |
| 2 |
0 |
0 |
0 |
0 |
| 3 |
0 |
0 |
0 |
0 |
| 4 |
0 |
0 |
0 |
0 |
| 5 |
0 |
0 |
0 |
0 |
| 6 |
0 |
0 |
0 |
0 |
|
| |
|
Animal No.
|
SCORE FOR POSITIVE CONTROL
|
|
Erythema and Escher formation
|
Edema
|
| 0 hr |
48 hrs |
0 hr |
48 hrs |
| 1 |
0 |
+5 |
0 |
0 |
| 2 |
0 |
+5 |
0 |
0 |
| 3 |
0 |
+5 |
0 |
0 |
| 4 |
0 |
+5 |
0 |
0 |
| 5 |
0 |
+5 |
0 |
0 |
| 6 |
0 |
+5 |
0 |
0 |
|
| |
| CONCLUSION |
| The given cosmetic product did not show any irritation or edema at the site of application in rabbits. |